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100050 - Statement - Consolidated Balance Sheets (Parenthetical)
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100070 - Statement - Consolidated Statements of Operations and Other Comprehensive Loss
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100100 - Statement - Consolidated Statements of Cash Flows
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100120 - Disclosure - Summary of Significant Accounting Policies
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100130 - Disclosure - Property and Equipment, Net
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100140 - Disclosure - Fair Value of Financial Instruments
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100170 - Disclosure - Leases
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100180 - Disclosure - Equity Method Investment
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100220 - Disclosure - Preferred and Common Stock
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100240 - Disclosure - Net Loss per Share Attributable to Common Stockholders
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100260 - Disclosure - Related Party Transactions
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100280 - Disclosure - Subsequent Events
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100290 - Disclosure - Summary of Significant Accounting Policies (Policies)
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100300 - Disclosure - Summary of Significant Accounting Policies (Tables)
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100310 - Disclosure - Property and Equipment, Net (Tables)
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100320 - Disclosure - Fair Value of Financial Instruments (Tables)
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100340 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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100350 - Disclosure - Leases (Tables)
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100360 - Disclosure - Guide Acquisition (Tables)
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100370 - Disclosure - License Agreements (Tables)
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100380 - Disclosure - Stock Option and Grant Plan (Tables)
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100390 - Disclosure - Net Loss per Share Attributable to Common Stockholders (Tables)
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100400 - Disclosure - Income Taxes (Tables)
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100410 - Disclosure - Nature of the Business and Basis of Presentation - Additional Information (Details)
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100420 - Disclosure - Summary of Significant Accounting Policies - Reconciliation of Cash, Cash Equivalents, and Restricted Cash (Details)
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100430 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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100440 - Disclosure - Summary of Significant Accounting Policies - Estimated Useful Life of Property and Equipment (Details)
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100450 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment (Details)
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100460 - Disclosure - Property and Equipment, Net - Summary of Depreciation Expense Incurred (Details)
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100470 - Disclosure - Fair Value of Financial Instruments - Schedule of Fair Value of Financial Assets and Liabilities (Details)
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100480 - Disclosure - Fair Value of Financial Instruments - Additional Information (Details)
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100490 - Disclosure - Fair Value of Financial Instruments - Summarizes Other Income (Expense) Incurred Due To Changes In Fair Value Of Corporate Equity Securities Held (Details)
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100500 - Disclosure - Fair Value of Financial Instruments - Schedule of Calculation of Estimated Fair Value of Success Payment Liabilities (Details)
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100510 - Disclosure - Fair Value of Financial Instruments - Schedule of Change in Fair Value of Success Payment Liabilities Based on Level 3 Inputs (Details)
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100520 - Disclosure - Fair Value of Financial Instruments - Schedule of Change in Fair Value of Contingent Consideration Liabilities Based on Level 3 Inputs (Details)
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100530 - Disclosure - Fair Value of Financial Instruments - Schedule of Calculation of Estimated Fair Value of Contingent Consideration Liabilities (Details)
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100560 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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100570 - Disclosure - Accrued Expenses and Other Current Liabilities - Additional Information (Details)
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100580 - Disclosure - Leases - Additional Information (Details)
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100590 - Disclosure - Leases - Summary of Operating Lease Costs (Details)
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100600 - Disclosure - Leases - Summary of Lease Term and Discount Rate (Details)
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100610 - Disclosure - Leases - Summary of Lease Costs Included in Measurement of Lease Liabilities (Details)
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100620 - Disclosure - Leases - Summary of Future Minimum Lease Payments of Operating Leases (Details)
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100630 - Disclosure - Leases - Summary of Future Minimum Payments Related to Equipment Financing Obligations (Details)
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100640 - Disclosure - Leases - Summary of Future Minimum Payments Related to Equipment Financing Obligations (Parenthetical) (Details)
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100650 - Disclosure - Leases - Summary of Principal and Interest Portions (Details)
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100660 - Disclosure - Equity Method Investment - Additional Information (Details)
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100670 - Disclosure - Guide Acquisition - Additional Information (Details)
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100680 - Disclosure - Guide Acquisition - Summary of Transaction Price Determined and Allocated (Details)
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100690 - Disclosure - License Agreements - Harvard License Agreement - Additional Information (Details)
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100700 - Disclosure - License Agreements - Harvard License Agreement - Success Payment Liability (Details)
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100710 - Disclosure - License Agreements - Harvard License Agreement - Change in Fair Value of Success Payment Liability (Details)
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100720 - Disclosure - License Agreements - Broad License Agreement - Additional Information (Details)
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100730 - Disclosure - License Agreements - Broad License Agreement - Success Payment Liability (Details)
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100740 - Disclosure - License Agreements - Broad License Agreement - Change in Fair Value of Success Payment Liability (Details)
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100750 - Disclosure - License Agreements - Editas License Agreement - Additional Information (Details)
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100760 - Disclosure - License Agreements - Bio Palette License Agreement - Additional Information (Details)
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100770 - Disclosure - Collaboration and License Agreements - Additional Information (Details)
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100780 - Disclosure - Preferred and Common Stock - Additional Information (Details)
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100790 - Disclosure - Stock Option and Grant Plan - Additional Information (Details)
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100800 - Disclosure - Stock Option and Grant Plan - Summary of Stock-based Compensation Expense (Details)
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100810 - Disclosure - Stock Option and Grant Plan - Schedule of Assumptions Used in Black-Scholes Option-Pricing Model for Stock Options Granted (Details)
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100820 - Disclosure - Stock Option and Grant Plan - Summary of Option Activity Under Equity Award Plans (Details)
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100830 - Disclosure - Stock Option and Grant Plan - Summary of Restricted Stock Activity (Details)
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100850 - Disclosure - Net Loss per Share Attributable to Common Stockholders - Summary of Computation of Basic and Diluted Net Loss per Share Attributable to Common Stockholders (Details)
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100860 - Disclosure - Income Taxes - Schedule of Reconciliation of Income Tax Expense (Details)
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100870 - Disclosure - Income Taxes - Schedule of Components of Deferred Taxes (Details)
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100880 - Disclosure - Income Taxes - Additional Information (Details)
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100890 - Disclosure - Related Party Transactions - Additional Information (Details)
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100900 - Disclosure - Employee Benefits - Additional Information (Details)
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